Primary neuroendocrine carcinoma of the liver: An autopsy case.

Autor: Kaya, Gürkan, Pasche, Christophe, Osterheld, Maria-Chiara, Chaubert, Pascal, Fontolliet, Charlotte
Předmět:
Zdroj: Pathology International; Nov2001, Vol. 51 Issue 11, p874-878, 5p, 6 Black and White Photographs
Abstrakt: An autopsy case of primary hepatic neuroendocrine carcinoma is described. A 72-year-old man had a large tumor mass measuring 22 cm in its greatest diameter and localized to the right, left and caudal lobes of the non-cirrhotic liver. Microscopically, the tumor was composed of middle-sized pleomorphic cells organized in ribbons or trabeculae, with scanty intersecting fibrous septae. Immunohistochemically, the tumor cells were positive for multikeratin C11, chromogranin A and synaptophysin. The patient also had metastases in the bone marrow. No alternative primary source of endocrine tumor was detected. The patient died 4 days after presentation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index