Acne rosacea associated imatinib mesylate in a gastrointestinal stromal tumor patient.

Autor: Demirci, Umut, Coskun, Ugur, Erdem, Ozlem, Ozturk, Banu, Bilge Yilmaz, Isilay, Benekli, Mustafa, Buyukberber, Suleyman
Předmět:
Zdroj: Journal of Oncology Pharmacy Practice; Sep2011, Vol. 17 Issue 3, p285-287, 3p, 2 Color Photographs
Abstrakt: Tyrosine kinase inhibitors (TKIs) are targeted treatments for various cancers. Skin toxicities are one of the most common nonhematological side-effects of TKIs. We report an imatinib mesylate (IM) induced hyperpigmented acne rosacea (AR) and sunitinib-induced palmar hyperkeratosis in the case with gastrointestinal stromal tumor. AR was arisen due to the discontinuation of IM. To the best of our knowledge, this kind of cutaneous side-effect with IM has not been documented previously. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index