Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans.
Autor: | Taísa Magnani Dinamarco, Maria Helena S. Goldman |
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Zdroj: | Biochemical Society Transactions; Oct2011, Vol. 39 Issue 5, p1544-1548, 5p |
Abstrakt: | FOH (farnesol), a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, has been shown to inhibit proliferation and induce apoptosis. We have been using Aspergillus nidulans and FOH as a model system and cell death stimulus, respectively, aiming to understand by which means filamentous fungi are driven towards cell death. Here, we review some of our findings about FOH-induced cell death in A. nidulans. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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