Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans.

Autor: Taísa Magnani Dinamarco, Maria Helena S. Goldman
Předmět:
Zdroj: Biochemical Society Transactions; Oct2011, Vol. 39 Issue 5, p1544-1548, 5p
Abstrakt: FOH (farnesol), a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, has been shown to inhibit proliferation and induce apoptosis. We have been using Aspergillus nidulans and FOH as a model system and cell death stimulus, respectively, aiming to understand by which means filamentous fungi are driven towards cell death. Here, we review some of our findings about FOH-induced cell death in A. nidulans. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index