Effects of Pro-Gly-Pro Tripeptide on the Dopamine System.

Autor: Meshavkin, V., Batishcheva, E., Kost, N., Sokolov, O., Trufanova, A., Samonina, G.
Předmět:
Zdroj: Bulletin of Experimental Biology & Medicine; Aug2011, Vol. 151 Issue 4, p429-431, 3p
Abstrakt: Tripeptide Pro-Gly-Pro interacted with dopamine receptors in vitro and reduced behavioral manifestations of apomorphine-induced hyperfunction of the dopamine system in verticalization, stereotypy, and yawning tests. Presumably, the behavioral effects of Pro-Gly-Pro tripeptide were mediated through post- and presynaptic D and D receptors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index