| Autor: |
Kruszynski, Marian, Tsui, Ping, Stowell, Nicole, Luo, Jinquan, Nemeth, Jennifer F., Das, Anuk M., Sweet, Raymond, Heavner, George A. |
| Zdroj: |
Journal of Peptide Science; May2006, Vol. 12 Issue 5, p354-360, 7p |
| Abstrakt: |
Human monocyte chemoattractant protein 1 (MCP-1, CCL2) is a 8.6-kDa protein that has been implicated in a number of diseases including atherosclerosis, rheumatoid arthritis, chronic obstructive pulmonary disease and cancer. As part of a program to identify antibodies against MCP-1, we synthesized site-specific, biotinylated human MCP-1 analogs to be used for panning of an antibody phage display library. In contrast to material obtained from random biotinylation, the site-specific biotinylated analogs were homogeneous and retained full activity. Copyright © 2005 European Peptide Society and John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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