Chylous effusion presenting in a 37-year-old woman with severe hypothyroidism: a case report.

Autor: Koo, Kevin S. H., Barnard, Rand, Kagawa, Frank T., Weichia Chen, Hinojosa, Irma, Koo, Kevin Sh, Chen, Weichia
Předmět:
Zdroj: Journal of Medical Case Reports; 2010, Vol. 4 Issue 1, p1-5, 5p
Abstrakt: Introduction: We report what is to the best of our knowledge the second adult case of chylothorax clearly associated with severe hypothyroidism in the English-language medical literature. To the best of our knowledge, this is the first case of its kind reported without a prior history of malignancy.Case Presentation: A 37-year-old Hispanic woman with no reported significant past medical history initially presented with shortness of breath and inability to lose weight. She was found to have a large chylous effusion requiring chest-tube drainage, as well as severe hypothyroidism. After several weeks of thyroid hormone-replacement therapy, the formation of chylous pleural fluid in the patient greatly diminished, and the chest tube was removed. Upon long-term follow-up her minimal residual effusion remains stable on serial chest radiographs.Conclusion: Although the exact pathophysiologic relation between low thyroid hormone levels and chyle formation remains to be elucidated, hypothyroidism should be a diagnostic consideration in patients with chylous effusions, especially those refractory to conventional treatments. [ABSTRACT FROM AUTHOR]
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