Aberrant microRNA expression in the development of breast carcinoma.

Autor:	WU Qian, LI HaiLing, LU JiaFeng, GE QingYu, LU ZuHong
Předmět:	NON-coding RNA GENE expression CARCINOGENESIS BREAST cancer diagnosis TUMOR growth ONCOGENES TUMOR markers METASTASIS CANCER invasiveness
Zdroj:	Chinese Science Bulletin; Nov2010, Vol. 55 Issue 31, p3517-3526, 10p
Abstrakt:	microRNAs, a class of small non-coding regulatory RNAs, are involved in oncogenesis and cancer development. Studies have shown that aberrant miRNA expression occurs in breast cancer and is associated with specific clinicopathological features. Some miRNAs might act as suppressor genes or oncogenes, which can be considered as novel markers for breast cancer diagnosis and as prognostic factors. Here we present a review of recent discoveries on miRNAs involved in breast cancer tumorigenesis, invasion, and metastasis. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink