| Autor: |
Ramazzotti, Anna, Pepe, Alessia, Positano, Vincenzo, Rossi, Giuseppe, De Marchi, Daniele, Brizi, Maria Gabriella, Luciani, Antongiulio, Midiri, Massimo, Sallustio, Giuseppina, Valeri, Gianluca, Caruso, Vincenzo, Centra, Michele, Cianciulli, Paolo, De Sanctis, Vincenzo, Maggio, Aurelio, Lombardi, Massimo |
| Zdroj: |
Journal of Magnetic Resonance Imaging; Jul2009, Vol. 30 Issue 1, p62-68, 7p |
| Abstrakt: |
Purpose To assess the transferability of the magnetic resonance imaging (MRI) multislice multiecho T2* technique for global and segmental measurement of iron overload in thalassemia patients. Materials and Methods Multiecho T2* sequences were installed on six MRI scanners. Five healthy subjects ( n = 30) were scanned at each site; five thalassemia major (TM) patients were scanned at the reference site and were rescanned locally ( n = 25) within 1 month. T2* images were analyzed using previously validated software. Results T2* values of healthy subjects showed intersite homogeneity. On TM patients, for global heart T2* values the correlation coefficient was 0.97, coefficients of variation (CoVs) ranged from 0.04-0.12, and intraclass coefficients (ICCs) ranged from 0.94-0.99. The mean CoV and ICC for segmental T2* distribution were 0.198 and 88, respectively. Conclusion The multislice multiecho T2* technique is transferable among scanners with good reproducibility. J. Magn. Reson. Imaging 2009;30:62-68. © 2009 Wiley-Liss, Inc. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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