| Autor: |
HOLLMAN, G, GULLBERG, M, EK, A.-C, ERIKSSON, M, OLSSON, A. G |
| Předmět: |
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| Zdroj: |
Journal of Internal Medicine; Apr2002, Vol. 251 Issue 4, p331-337, 7p, 3 Charts |
| Abstrakt: |
Objectives: The primary aim of this study was to analyse quality of life in adult patients with familial hypercholesterolaemia (FH), a genetic disorder with increased risk of coronary heart disease (CHD). Secondary aims were to find explanatory factors for quality of life and anxiety.Design: A descriptive cross-sectional design was used.Setting: Outpatients from lipid clinics at two university hospitals in Sweden were included. Patients with heterozygous FH and a randomly selected control group participated by filling out questionnaires.Subjects: Two hundred and eighty patients with heterozygous FH above 18 years of age were asked, and 212 of whom 185 were free of overt CHD, participated. Of a control group of 2980 persons 1485 were included for comparison.Methods: We used Likert-type questionnaires: the Quality of Life Index (QLI) consisting of four subscales, the Hospital Anxiety and Depression Scale (HAD), the Mastery Scale measuring coping and a questionnaire on health and lipids constructed for FH patients.Results: Patients with FH were significantly more satisfied with overall quality of life 21.8 +/- 0.3 (SEM) vs. controls 21.1 +/- 0.1 and this was also the case in three of four subscales, all differences P < 0.05. Anxiety about getting CHD was expressed amongst 86% of the patients with FH.Conclusions: Quality of life amongst patients with FH was at least as good as in controls but they were worried about getting CHD. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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