High glucose abolishes the antiproliferative effect of 17 β-estradiol in human vascular smooth muscle cells.

Autor: Shanhong Ling, Little, Peter J., Williams, Maro R.I., Dai, Aozhi, Hashimura, Kazuhiko, Jun-Ping Liu, Komesaroff, Paul A., Sudhir, Krishnankutty
Předmět:
Zdroj: American Journal of Physiology: Endocrinology & Metabolism; Apr2002, Vol. 45 Issue 4, pE746, 6p, 12 Graphs
Abstrakt: Examines the effects of 17 β-estradiol on human vascular smooth muscle cell (VSMC) proliferation under normal and high glucose concentrations. Assays of cell proliferation; Analysis of protein kinase C (PKC) activity; Involvement of PKC-β in the stimulatory effect of high glucose on VSMC proliferation.
Databáze: Complementary Index