Autor: |
Escribano, Luis, Orfao, Alberto, Villarrubia, Jesús, Díaz-Agustín, Beatriz, Cerveró, Carlos, Rios, Agustín, Velasco, José L., Ciudad, Juana, Navarro, José L., San Miguel, Jesús F. |
Předmět: |
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Zdroj: |
Analytical Cellular Pathology; 1998, Vol. 16 Issue 3, p151, 9p |
Abstrakt: |
The goal of the present paper was to define the immunophenotype of bone marrow mast cells (BMMC) from healthy controls and patients with hematologic malignancies (HM) based on the use of multiple stainings with monoclonal antibodies analyzed by flow cytometry. Our results show that BMMC from both groups of individuals display a similar but heterogenous immunophenotype. The overall numbers of BMMC are higher in the HM group of individuals (In summary, our results show that BMMC from both healthy controls and HM patients display a relatively heterogenous immunophenotype. Interestingly, we have observed clear differences between the immunophenotype of BMMC and MC from other tissues. This could be due either to the heterogeneity of human MC according to their tissue localization or to the sensitivity of the method used for antigen detection. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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