| Autor: |
Mair, R. W., Hrovat, M. I., Patz, S., Rosen, M. S., Ruset, I. C., Topulos, G. P., Tsai, L. L., Butler, J. P., Hersman, F. W., Walsworth, R. L. |
| Zdroj: |
Magnetic Resonance in Medicine; Apr2005, Vol. 53 Issue 4, p745-749, 5p |
| Abstrakt: |
The human lung and its functions are extremely sensitive to gravity; however, the conventional high-field magnets used for most laser-polarized 3He MRI of the human lung restrict subjects to lying horizontally. Imaging of human lungs using inhaled laser-polarized 3He gas is demonstrated in an open-access very-low-magnetic-field (<5 mT) MRI instrument. This prototype device employs a simple, low-cost electromagnet, with an open geometry that allows variation of the orientation of the imaging subject in a two-dimensional plane. As a demonstration, two-dimensional lung images were acquired with 4-mm in-plane resolution from a subject in two orientations: lying supine and sitting in a vertical position with one arm raised. Experience with this prototype device will guide optimization of a second-generation very-low-field imager to enable studies of human pulmonary physiology as a function of subject orientation. Magn Reson Med 53:745-749, 2005. © 2005 Wiley-Liss, Inc. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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