Baicalein attenuates oxidant stress in cardiomyocytes.

Autor: Zuo-Hui Shao, Vanden Hoek, Terry L., Yimin Qin, Becker, Lance B., Schumacker, Paul T., Chang-Qing Li, Dey, Lucy, Barth, Eugene, Halpern, Howard, Rosen, Gerald M., Chun-Su Yuan
Předmět:
Zdroj: American Journal of Physiology: Heart & Circulatory Physiology; Mar2002, Vol. 282 Issue 3, pH999, 8p, 1 Diagram, 10 Graphs
Abstrakt: Studies the antioxidative effects of baicalein in a chick cardiomyocyte model of reactive oxygen species (ROS) generation during hypoxia, simulated ischemia-reperfusion or mitochondrial complex III inhibition with antimycin A. Antioxidant effects of baicalein; Possible contribution of intracellular ROS generation to the pathogenesis of cellular injury; Mechanism of baicalein effect on reperfusion ROS.
Databáze: Complementary Index