Localization of estrogen receptor αα and progesterone receptor B in bovine cervix and vagina during the follicular and luteal phases of the sexual cycle.

Autor: Sağsöz, H, Akbalik, ME, Saruhan, BG, Ketani, MA
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Zdroj: Biotechnic & Histochemistry; Aug2011, Vol. 86 Issue 4, p262-271, 10p, 5 Color Photographs, 3 Charts
Abstrakt: The localization and distribution of estrogen receptors (ERαα) and progesterone receptors (PR-B) in the cervix and vagina of sexually mature bovines during the follicular and luteal phases of the sexual cycle were studied using immunohistocehmistry. The estrous cycle stage of 23 Holstein bovines was assessed by gross and histological appearance of ovaries and blood steroid hormone values. Tissue samples from cervix and vagina were fixed in 10% formaldehyde for routine histological processing. Nuclear staining for ERαα and PR-B was observed in the epithelial cells of the surface epithelium, stromal cells and smooth muscle cells. Generally, in the cervix, ERαα immunoreactivity was more intense in the epithelial and smooth muscle cells during the follicular phase and in the epithelial cells during the luteal phase ( p < 0.05). PR-B immunoreactivity was more intense in the epithelial and smooth muscle cells than in the superficial and deep stromal cells during the follicular and luteal phases ( p < 0.05). In the vagina, ERαα and PR-B immunoreactivities were more intense in the epithelial cells than in the connective tissue cells and smooth muscle cells during the follicular and luteal phases ( p < 0.05). These results indicated that the frequency and intensity of ERαα and PR-B immunoreactivity in the cervix and vagina of bovines varied according to the cervical and vaginal cell types and the phases of the sexual cycle. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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