| Autor: |
Heffron, Renee, Chao, Ann, Mwinga, Alwyn, Sinyangwe, Sylvester, Sinyama, Alex, Ginwalla, Rokaya, Shields, J Mark, Kafwembe, Emmanuel, Kaetano, Lovemore, Mulenga, Chanda, Kasongo, Webster, Mukonka,, Victor, Bulterys, Marc |
| Předmět: |
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| Zdroj: |
Sexually Transmitted Infections; Jun2011, Vol. 87 Issue 4, p283-288, 6p, 3 Charts, 1 Graph |
| Abstrakt: |
Background More insight is needed regarding risk factors for prevalent and incident HIV-1 infection among male farm workers in Sub-Saharan Africa to control the HIV-1 epidemic. Methods Male farm workers were recruited from a sugar estate in Zambia to participate in a prospective cohort study. Questionnaire data were collected via interview, and testing was conducted for HIV-1, herpes simplex virus type 2 (HSV-2), and syphilis infection at baseline and follow-up between May 2006 and September 2007. Results Among 1062 workers enrolled, HIV-1 prevalence at baseline was 20.7%. Testing HSV-2 seropositive (adjusted odds ratio (AOR) 5.4, 95% CI 3.6 to 8.1), self-reported genital ulcers in the past year (AOR 2.8, 95% CI 1.9 to 4.2), and being widowed (AOR 3.7, 95% CI 2.0 to 6.9) were significantly associated with prevalent HIV-1 infection. The HIV-1 incidence among 731 initially negative participants with at least one follow-up visit was 4.1 per 1000 person-months (95% CI 2.6 to 5.7); seroconversion was independently associated with prevalent HSV-2 infection (adjusted hazard ratio (AHR) 2.4, 95% CI 1.0 to 5.8) and incident HSV-2 infection (AHR 18.0, 95% CI 4.2 to 76.3). HIV-1 prevalence and incidence rates were similar among migrant and non-migrant workers. Conclusions HIV-1 prevalence and incidence were high, and HSV-2 infection was a risk factor for HIV-1 acquisition. There is an urgent need to expand HIV-1 prevention programmes tailored to farm workers and their communities. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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