Synthesis and biological evaluation of - n[4-(2- trans-[([2,6-diamino-4(3 H)-oxopyrimidin-5-yl]methyl)thio]cyclobutyl)benzoyl] -l-glutamic acid a novel 5-thiapyrimidinone inhibitor of dihydrofolate reductase.

Autor: Varney, Michael D., Romines, William H., Boritzki, Theodore, Margosiak, Stephen A., Bartlett, Charlotte, Howland, Eleanor J.
Zdroj: Journal of Heterocyclic Chemistry; Sep1995, Vol. 32 Issue 5, p1493-1498, 6p
Databáze: Complementary Index
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