Autor: |
Ryschich, Eduard, Jesnowski, Ralf, Ringel, Jörg, Harms, Walter, Fabian, Oliver V., Saller, Robert, Schrewe, Michael, Engel, Alexander, Schmidt, Jan, Löhr, Matthias |
Zdroj: |
International Journal of Cancer; Feb2005, Vol. 113 Issue 4, p649-653, 5p |
Abstrakt: |
Local therapy of pancreatic cancer with microencapsulated CYP2B1-producing cells and ifosfamide showed an effect both on the primary tumor and on distant metastatases. This possibly represents a consequence of the activation of immune response. Other studies have demonstrated that local tumor irradiation leads to the activation of the intratumoral lymphocyte infiltration. The aim of our study was to investigate the efficacy of the combined therapy with low-dose irradiation, ifosfamide and CYP2B1-producing cells. Syngenic pancreatic cancer was induced in 38 Lewis-rats by subcutaneous inoculation of 1 × 10 [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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