Autor: |
GRAFF, JOHANNES, DOHOON KIM, DOBBIN, MATTHEW M., Li-HUEI TSAI |
Předmět: |
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Zdroj: |
Physiological Reviews; Apr2011, Vol. 91 Issue 2, p603-649, 47p |
Abstrakt: |
The article offers information on the epigenetic mechanisms of gene expression in physiological and pathological brain processes. It states that the deregulation of epigenetic regulation has been involved in a number of neurodevelopmental disorders, including Rett Syndrome, Fragile X and Schizophrenia. It mentions that the most common neurodegenerative disorder is Alzheimer's disease as neurons are progressively lost during disease progression from the hippocampus, cortex and other regions. |
Databáze: |
Complementary Index |
Externí odkaz: |
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