| Autor: |
Schuster, B. G., Jackson, J. E., Milhous, W., Obijiofor, C. N., Okunji, C. O., Losos, E., Ayafor, J. F., Iwu, M. M. |
| Předmět: |
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| Zdroj: |
Pharmaceutical Biology; Oct99 Supplement, Vol. 37, p84, 16p, 2 Diagrams |
| Abstrakt: |
The main focus of the African ICBG project is the establishment of an integrated program for the discovery of biologically active plants for drug development and biodiversity conservation, and at the same time ensure that local communities and source countries derive maximum benefits for their biological resources and their intellectual contribution. Although the project has three main sub-themes (biodiversity conservation, sustainable development and drug discovery), integration was emphasized from the conception of the program and has remained a fundamental point in the execution of various projects under this program. As a result, the African ICBG program differs in many ways from similar projects elsewhere. The African ICBG is a collaboration of the Walter Reed Army Institute of Research, Washington, DC (WRAIR), Bioresources Development and Conservation Programme (BDCP), the Smithsonian Tropical Research Institute, and nine other institutions in Cameroon, Nigeria and the United States of America. Scientists from the participating developing countries are involved in all aspects of the program so that information, principles and procedures developed during this work will be internalized in Africa and extended beyond the duration of the proposed project. The drug discovery component has yielded many lead compounds with potential for the treatment of malaria, leishmaniasis, trypanosomiasis, trichomonas, opportunistic infections, AIDS and other viral infections. Activity of some of the compounds is being optimized through chemical modifications. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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