Effects of diffuse fatty infiltration of the liver on portal vein flow hemodynamics.

Autor: Balci, Ali, Karazincir, Sinem, Sumbas, Haldun, Oter, Yasemin, Egilmez, Ertugrul, Inandi, Tacettin
Zdroj: Journal of Clinical Ultrasound; Mar2008, Vol. 36 Issue 3, p134-140, 7p
Abstrakt: Purpose: To investigate the effects of various degrees of diffuse fatty infiltration of the liver on portal vein blood flow with Doppler sonography. Methods: One hundred forty subjects were examined with color and spectral Doppler sonography. The subjects were divided into 4 groups of 35 subjects each according to the degree (normal, grade 1, grade 2 and grade 3) of hepatic fatty infiltration assessed on gray-scale images. The portal vein pulsatility index (VPI) and time-averaged mean flow velocity (MFV) were calculated for each subject. VPI was calculated as (peak maximum velocity - peak minimum velocity) / peak maximum velocity. Results: VPI and MFV values were, respectively, 0.32 +/- 0.06 and 16.8 +/- 2.6 cm/second in the normal group, 0.27 +/- 0.07 and 14.2 +/- 2.2 cm/second in the group with grade 1 fatty infiltration, 0.22 +/- 0.06 and 12.2 +/- 1.8 cm/second in the group with grade 2 fatty infiltration, and 0.18 +/- 0.04 and 10.8 +/- 1.5 cm/second in the group with grade 3 fatty infiltration. There was a negative inverse correlation between the grade of fatty infiltration and both VPI (f = 55.3, p < 0.001) and MFV (f = 43.9, p < 0.001). Conclusion: The pulsatility index and mean velocity of the portal vein blood flow decrease as the severity of fatty infiltration increases. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index