Skeletal muscle remodeling in response to alpine skiing training in older individuals.

Autor:	Narici, M. V., Flueck, M., Koesters, A., Gimpl, M., Reifberger, A., Seynnes, O. R., Niebauer, J., Rittweger, J., Mueller, E.
Předmět:	ASTHENIA MUSCULAR atrophy STRIATED muscle physiology ANALYSIS of variance STATISTICAL correlation EXERCISE physiology EXERCISE tests GAIT in humans SKIING MUSCLE contraction MUSCLES HEALTH outcome assessment PROBABILITY theory RESEARCH funding STATISTICS STRIATED muscle TORQUE DATA analysis CASE-control method OLD age THERAPEUTICS
Zdroj:	Scandinavian Journal of Medicine & Science in Sports; Aug2011 Supplement, Vol. 21, p23-28, 6p, 1 Black and White Photograph, 1 Chart, 2 Graphs
Abstrakt:	This study investigated whether regular alpine skiing could reverse sarcopenia and muscle weakness in older individuals. Twenty-two older men and women (67 ± 2 years) underwent 12 weeks of recreational skiing, two to three times a week, each session lasting∼3.5 h. An age-matched, inactive group ( n=20, 67 ± 4 years) served as a control (CTRL). Before and after the training period, knee extensors muscle thickness ( T), pennation angle (θ) and fascicle length ( L) of the vastus lateralis muscle were measured by ultrasound. Maximum isokinetic knee extensor torque (MIT) at an angular velocity of 60°/s was measured by dynamometry. After the training, T increased by 7.1% ( P<0.001), L by 5.4% ( P<0.02) and θ by 3.4% ( P<0.05). The increase in T was matched by a significant gain in MIT (13.3%, P<0.001). No significant changes, except for a decrease in θ (2.1%, P<0.02), were found in the CTRL group. The gain in T in the training group correlated significantly with an increase in the focal adhesion kinase content, pointing to a primary role of this mechano-sensitive protein in sarcomere remodeling with muscle hypertrophy. Overall, the results show that alpine skiing is an effective intervention for combating sarcopenia and weakness in old age. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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