Inhibition of the hydrolytic and transpeptidase activities of rat kidney γ-glutamyl transpeptidase by specific monoclonal antibodies.

Autor: Bluvshtein, Evgenia, Glass, George A., Volohonsky, Gloria, Yaakubowitz, Margalit, Harness, Ella, Smorodinsky, Nechana I., Seidel, Albrecht, Frank, Heinz, Steinberg, Pablo, Stark, Avishay A.
Předmět:
Zdroj: European Journal of Biochemistry; Mar99 Part 2, Vol. 260 Issue 3, p844, 11p, 4 Black and White Photographs, 3 Charts, 9 Graphs
Abstrakt: Examines the isolation of monoclonal antibodies (mAb) against the native form of rat kidney upsilon-glutamyl transpeptidase (GGT). Inhibition of the enzyme activity of GGT in the mAb; Increase of the affinity of the donor GGT site; Importance of GGT identification for the hydrolytic and transpeptidase activities.
Databáze: Complementary Index