Overexpression of the Golgi-localized enzyme α-mannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway.

Autor: Oh-eda, Masayoshi, Nakagawa, Hiroaki, Akama, Tomoya O., Lowitz, Kevin, Misago, Masahiro, Moremen, Kelley W., Fukuda, Michiko N.
Předmět:
Zdroj: European Journal of Biochemistry; Mar2001, Vol. 268 Issue 5, p1280, 9p, 7 Color Photographs, 1 Diagram, 12 Graphs
Abstrakt: Examines Golgi-localized alpha-mannosidase IIx overexpression of the N-glycan-processing pathway on the Chinese hamster ovary cells. Immunocytochemistry of alpha-mannosidase IIX on HeLa cells; Inhibition of swinsonine on the hydrolyzes of protein A fusion; Identification of the structural analysis.
Databáze: Complementary Index