Sugar-based tertiary amino gemini surfactants with a vesicle-to-micelle transition in the endosomal pH range mediate efficient transfection in vitro.

Autor: Fielden, Matthew L., Perrin, Christele, Kremer, Andreas, Bergsma, Mark, Stuart, Marc C., Camilleri, Patrick, Engberts, Jan B.F.N.
Předmět:
Zdroj: European Journal of Biochemistry; Mar2001, Vol. 268 Issue 5, p1269, 11p, 3 Black and White Photographs, 1 Diagram, 8 Graphs
Abstrakt: Examines the sugar gemini surfactants transition of the endosomal pH range transfection on the Chinese hamster ovary cells. Transfection efficiency; Implication of the micelles formation between gemini surfactant and membrane phospholipids for fusogenic agents; Effects of pH reduction on the hydrocarbon region of the DNA-surfactant complex.
Databáze: Complementary Index