A RANDOMIZED STUDY COMPARING THE EFFECT OF STANDARD VERSUS SHORT INCUBATION OF SPERM AND OOCYTE ON SUBSEQUENT PREGNANCY AND IMPLANTATION RATES FOLLOWING IN VITRO FERTILIZATION EMBRYO TRANSFER.

Autor: Swenson, K., Summers-Chase, D., Choe, J. K., Chec, M. L
Předmět:
Zdroj: Archives of Andrology; Jul/Aug2000, Vol. 45 Issue 1, p73-77, 5p, 3 Charts
Abstrakt: Some data suggest that some sperm are associated with a toxic product that lowers embryo implantation rates when these sperm come in contact with the zona pellucida. The possibility exists that shortening the incubation time could improve pregnancy rates. A randomized prospective study was initiated to evaluate pregnancy and implantation rates with transfer of embryos formed by conventional overnight vs short (2-h) co-incubation of sperm and oocytes. The clinical and viable pregnancy rates were 41 and 29% for conventional co-incubation versus 30 and 30% for short co-incubation. Implantation rates were also similar (17.9 vs 17.8%). Short incubation does not seem to impact any advantage over conventional co-incubation techniques in couples undergoing in vitro fertilization where the male factor is normal. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index