Haemodynamic response following a 10% topload infusion of Hemolink in conscious, anaesthetized and treated spontaneously hypertensive rats.

Autor: Ning, J., Wong, L.T., Christoff, B., Carmichael, F.J.L., Biro, G.P.
Předmět:
Zdroj: Transfusion Medicine; Mar2000, Vol. 10 Issue 1, p13, 10p, 1 Chart, 8 Graphs
Abstrakt: Examines the systemic hemodynamic response to Hemolink (HLK), a hemoglobin-based oxygen carrier (HBOC) in spontaneously hypertensive rats. Pharmacological effects of HLK in animal experiments; Use of a topload infusion strategy to evaluate the toxicological effects of HBOC in human volunteers; Administration of nifedipine in the rats.
Databáze: Complementary Index