A comparative study of chlorhexidine gel, metronidazole placed post scaling and root planning and unplaced.

Autor: Bhardwaj, Anshul, Kudva, Praveen, Tabasum, Syeda Tawkhira
Předmět:
Zdroj: Journal of International Oral Health; 2010, Vol. 2 Issue 1, p1-8, 8p, 3 Charts, 3 Graphs
Abstrakt: Aim and objectives: The present study evaluated and compared the clinical effects of topical sub gingival application following scaling & root planing (SRP) of a new biodegradable xanthan based chlorhexidine (CHX) gel as compared with a gel containing CHX and metronidazole and SRP alone. Material and methods: In study three clinical parameters i.e.; plaque index (PI), gingival index (GI) and probing depth (PD) and five microbiological parameters i.e.; porphyromonas gingivalis, prevotella, actinobacillus actinomycetemcomitans, capnocytophaga and fusobacterium were compared at baseline and at 4 weeks for three different groups. Study was conducted on 10 patients of both genders with age ranging from 40-60 years. These subjects were having chronic generalized periodontitis with minimum three sites in the molar region and with 5-8 mm PD in different sexant. 30 sites were divided into 3 groups (10 sites in each group). Group I where xanthan based CHX gel was placed, group II where combination of CHX and metronidazole gel was placed and group III where SRP alone was placed. Treatment was completed, in 2 visits spread over 4 weeks. Results: Results showed statistically highly significant differences in GI at 4 weeks in all three groups when compared with baseline. Highly significant differences were noted in PI at 4 weeks in all three groups when compared with baseline. Significant differences were noted in PD at 4 weeks in all three groups when compared with baseline. Conclusions:Xanthan based chlorhexidine gel (Chlosite gel) showed maximum reduction in percentage of occurrence for Porphyromonas gingivalis and almost same reduction for Actinobacillus actinomycetemcomitans and Fusobacterium species. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index