| Abstrakt: |
Intersphincteric resection (ISR) is regarded as the most extreme form of resection of ultralow rectal cancers. ISR for low rectal carcinoma is a demanding operation, whose outcome in terms of morbidity, mortality, local recurrence rates, survival, functional results and patients' quality of life can vary greatly. Postoperative morbidity and mortality rates, as well as oncological results, are relatively acceptable, with a mean operative mortality and anastomotic leak rate following ISR of 1.6% and 10.5% respectively, while local recurrence rate is 9. 5% and systemic recurrence rate 9.3%. Patients must be counselled to expect inferior functional results compared with those normally experienced following anterior resection, although the formation of a j-pouch can improve these symptoms. Careful case selection with appropriate assessment of anorectal function is recommended. Neoadjuvant radiotherapy could improve rates of local recurrence, but may have a negative impact on postoperative function. [ABSTRACT FROM AUTHOR] |
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