| Autor: |
Hui, Thomas T., Fass, Steven M., Giurgiu, Dan I., Iida, Atsushi, Takagi, Sumito, Phillips, Edward H. |
| Předmět: |
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| Zdroj: |
Archives of Surgery; May2000, Vol. 135 Issue 5, p545, 5p |
| Abstrakt: |
Hypothesis: Nausea associated with gastroesophageal reflux disease is cured by laparoscopic Nissen fundoplication (LNF). Design: Prospective cohort study of unselected patients who underwent LNF from January 1, 1995, through March 31, 1999. Patients were followed up by a physician for 6 to 36 months. Setting: A large community teaching hospital. Patients: One hundred consecutive patients with gastroesophageal reflux disease who underwent LNF; all patients were followed up. Patients were grouped according to the presence (group A, n=33) or absence (group B, n=67) of preoperative nausea. Interventions were LNF, esophageal manometry, 24-hour pH monitoring, and nuclear gastric emptying studies. Main Outcome Measures: Resolution of symptoms after LNF. Results: Nausea was the most common atypical symptom of gastroesophageal reflux disease, occurring in 33 patients (33%). There were no differences in esophageal manometry or 24-hour pH results between groups. There was a female preponderance in group A (55% vs 33%; P=.003). Patients in group A had a higher prevalence of preoperative dysphagia (P=.02). Patients with persistent postoperative nausea had a higher prevalence of cough (P=.003) and dysphagia (P=.009). The LNF was more effective in reducing heartburn (95% reduction) and regurgitation (95% reduction) than cough and dysphagia (60% reduction). There was a 79% reduction in the number of patients with nausea (33 to 7; P<.001). Conclusion: Laparoscopic Nissen fundoplication is effective in eliminating nausea associated with gastroesophageal reflux disease and is not contraindicated in these patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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