| Autor: |
Altman, Jerald S., Haupert, Michael S., Hamaker, Ronda A., Belenky, Walter M. |
| Předmět: |
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| Zdroj: |
Archives of Otolaryngology - Head & Neck Surgery; Nov98, Vol. 124 Issue 11, p1233, 4p |
| Abstrakt: |
Objective: To determine the efficacy of phenylephrine hydrochloride, a topical vasoconstrictor, in preventing tympanostomy tube obstruction. Design: Prospective, randomized, double-blind, controlled trial of patients undergoing myringotomy with tympanostomy tube insertion. Setting: Academic, tertiary referral medical center. Patients: Two hundred eight patients were enrolled in the study; 157 patients (310 ears) returned for postoperative evaluation. Interventions: Myringotomy with tympanostomy tube insertion was performed in all ears: 139 control ears received ototopical antibiotics and 171 treatment ears received ototopical antibiotics plus topical phenylephrine. Main Outcome Measure: Postoperative tympanostomy tube obstruction. Results: The overall incidence of tympanostomy tube obstruction was 5.2%: 8.6% in the control group and 2.3% in the treatment group. The treatment group demonstrated an odds ratio of 0.25 (95% confidence interval, 0.08-0.78; P=.02). Conclusion: The use of phenylephrine following tympanostomy tube insertion greatly reduces the incidence of tube obstruction. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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