Prognostic value of laparoscopic ultrasound in patients with gastro-esophageal cancer.

Autor: Flett, M. E., Lim, M. N., Bruce, D., Campbell, S. H., Park, K. G. M.
Předmět:
Zdroj: Diseases of the Esophagus; Sep-Dec2001, Vol. 14 Issue 3/4, p223-226, 4p, 1 Chart, 3 Graphs
Abstrakt: Forty-four patients with gastro-esophageal tumors regarded as resectable by conventional staging underwent laparoscopic ultrasonography (LUS). Following LUS, seven were found to be irresectable and were managed by palliative therapies. Thirty-seven patients proceeded to surgical exploration and 36 were resected (R0 80%, R1 11%, and R2 9%). All patients were reviewed until death or for a minimum of 24 months. Patients undergoing resection had a 62% 1-year survival (median 17 months; confidence intervals, CI 6–28). LUS defined nodal status indicated a trend toward prolonged survival in the node-negative group, median 22 months (CI 5–39), compared with 13 months (CI 6–20) in the node-positive group. Disease-free survival was greater in LUS node-negative patients at 29 months (CI 23–35) compared with node-positive patients at 13 months (CI 5–21) P =0.0083. LUS staging allows prediction of the likelihood of recurrence of gastro-esophageal malignancies. This may prove useful for the appropriate allocation of patients to primary and adjuvant therapies. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index