Non-myeloablative bone marrow transplantation in an adult with Wiskott–Aldrich syndrome.

Autor: Longhurst, Hilary J, Taussig, David, Haque, Tanzina, Court, Denise Syndercombe, Cavenagh, Jamie, Edgar, J. David, Helbert, Matthew R
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Zdroj: British Journal of Haematology; Feb2002, Vol. 116 Issue 2, p497-499, 3p
Abstrakt: Summary. Early bone marrow transplant is now standard treatment for infants with severe immunodeficiencies such as Wiskott–Aldrich Syndrome (WAS), but results in older children and adults are poor. Non-myeloablative transplant has shown promise in the treatment of older children, who are likely to have active infections and organ damage. We describe a non-myeloablative transplant of a 26-year-old man with WAS, undertaken because of severe infections and vasculitis. Partial engraftment and immunorestoration were achieved. The patient is well 1 year post transplantation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index