Autor: |
Pier, Gerald B., Grout, Martha, Zaidi, Tanweer, Meluleni, Gloria, Mueschenborn, Simone S., Banting, George, Ratcliff, Rosemary, Evans, Martin J., Colledge, William H. |
Předmět: |
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Zdroj: |
Nature; 5/7/1998, Vol. 393 Issue 6680, p79, 4p, 6 Black and White Photographs, 12 Graphs |
Abstrakt: |
Investigates the possibility that typhoid fever could be a disease where homozygous mutations in the fibrosis transmembrane conductance regulator (CFTR) occurs. How in the heterozygous state, increased resistance to infectious diseases may maintain mutmant CFTR alleles at high levels in selected population; Evidence indicating that Salmonella typhi uses CFTR for entry into epithelial cells; The conclusion of the research. |
Databáze: |
Complementary Index |
Externí odkaz: |
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