Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse effects.

Autor: Tamminga, Wim J., Wemer, Johan, Oosterhuis, Berend, Wieling, Jaap, Touw, Daan J., de Zeeuw, Rokus A., de Leij, Lou F.M.H., Jonkman, H.G.
Předmět:
Zdroj: British Journal of Clinical Pharmacology; May2001, Vol. 51 Issue 5, p471, 4p
Abstrakt: Evaluates the use of mephenytoin as a probe for CYP2C19 phenotyping. Urinary (S)-mephenytoin to (R)-mephenytoin ratio; Risk of incorrect classification; Intraindividual reproducibility of the ratio.
Databáze: Complementary Index