Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse effects.
Autor: | Tamminga, Wim J., Wemer, Johan, Oosterhuis, Berend, Wieling, Jaap, Touw, Daan J., de Zeeuw, Rokus A., de Leij, Lou F.M.H., Jonkman, H.G. |
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Zdroj: | British Journal of Clinical Pharmacology; May2001, Vol. 51 Issue 5, p471, 4p |
Abstrakt: | Evaluates the use of mephenytoin as a probe for CYP2C19 phenotyping. Urinary (S)-mephenytoin to (R)-mephenytoin ratio; Risk of incorrect classification; Intraindividual reproducibility of the ratio. |
Databáze: | Complementary Index |
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