A basic residue at position 36p of the propeptide is not essential for the correct folding and subsequent autocatalytic activation of prochymosin.

Autor: Francky, Andrej, Francky, Bojana Mozetic, Strukelj, Borut, Gruden, Kristina, Ritonja, Anka, Krizaj, Igor, Kregar, Igor, Pain, Roger H., Pungercar, Joze
Předmět:
Zdroj: European Journal of Biochemistry; Apr2001, Vol. 268 Issue 8, p2362, 7p, 5 Diagrams, 3 Graphs
Abstrakt: Investigates the significance of a basic residue at position 36p of the propeptide in the folding and autocatalytic activation of prochymosin. Stabilization of the propeptide--enzyme interaction; Description of chymosin; Secretion of chymosin by the mucosal cells.
Databáze: Complementary Index