| Autor: |
Towae, Frank, Juenger, Claus, Mudra, Harald, Glunz, Hans-Georg, Hauptmann, Eugen, Grube, Eberhard, Voigtländer, Thomas, Bauer, Timm, Zeymer, Uwe, Senges, Jochen, Gitt, Anselm Kai, Zahn, Ralf |
| Předmět: |
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| Zdroj: |
Acute Cardiac Care; Mar2011, Vol. 13 Issue 1, p35-39, 5p, 2 Charts, 4 Graphs |
| Abstrakt: |
Aim of the study: To examine the development of door-to- angiography time (DTA) and to evaluate the impact of door-to-angiography time in patients with ST-elevation myocardial infarction (STEMI) on hospital and one-year mortality. Methods and Results: From 1994 to 2008, 5078 patients (pts) and known DTA with acute ST-elevation myocardial infarction were enrolled into the MITRAplus and OPTAMI registry in Germany. Our data showed a reduction of the door-to- angiography time from 80 min to 64 min in the last 14 years ( P < 0.001). Over 80% of patients received an angiography less than two hours after admission. The main predictor of a shorter door-to-balloon time was a hypotension with a blood pressure lower than 100 mmHg (OR 1.46, 95%CI: 1.08--1.91). Whereas a history of prior myocardial infarction (OR 0.61, 95%CI: 0.45--0.84), a previous coronary bypass grafting (OR 0.55, 95%CI: 0.33--0.91), age older than 75 years (OR 0.78, 95%CI: 0.62--0.99) and a pre-hospital delay more than three hours (OR 0.78, 95%CI: 0.66--0.93) were independent predictors for a longer of the door-to-balloon time. In the multivariate regression analysis no influence was detected of door-to-angiography time on hospital or one-year mortality. Conclusion: The DTA decreased in the last 14 years and is actually very short in Germany. We indentified predictors of a longer door-to-angiography time in clinical practice. Given the overall short in-hospital delay, the observed door-to-angiography time did not have influence on hospital and mid term mortality. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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