Transcription inhibitors stimulate translation of 5′ TOP mRNAs through activation of S6 kinase and the mTOR/FRAP signalling pathway.

Autor: Loreni, Fabrizio, Thomas, George, Amaldi, Francesco
Předmět:
Zdroj: European Journal of Biochemistry; Nov2000 Part 2, Vol. 267 Issue 22, p6594-6601, 8p
Abstrakt: Studies the effect of transcription inhibitors on the polysomal localization of 5' terminal oligopyrimidine (TOP) mRNA. mRNA recruitment on polysomes during actinomycin D treatment; Effect of actinomycin D on TOP mRNA localization; Suppression of actinomycin D effect by rapamycin pretreatment.
Databáze: Complementary Index