| Autor: |
Xiaohui Xu, Sharma, Ravi K., Talbott, Evelyn O., Zborowski, Jeanne V., Rager, Judy, Arena, Vincent C., Dan Volz, Conrad |
| Předmět: |
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| Zdroj: |
International Archives of Occupational & Environmental Health; Mar2011, Vol. 84 Issue 3, p251-257, 7p, 1 Diagram, 3 Charts |
| Abstrakt: |
Purpose: Low birth weight has been associated with increased risks of mortality and/or morbidity in childhood and adulthood. Epidemiological studies suggest that maternal exposure to air pollution, especially particulate matter during pregnancy, is associated with an increased risk of delivering a low birth weight infant. The aim of this study is to explore the association between exposure to particulate matter (PM10) during pregnancy and term low birth weight (LBW: birth weight <2,500 g and gestation age ≥ 37 weeks). Methods: Birth data from the Allegheny County Health Department, Pittsburgh, PA, USA and PM10 air data generated with inverse-distance interpolation by RAND's Center for Population Health and Health Disparities, were obtained. The study population consisted of all term singleton live births (gestational age ≥ 37 weeks) born between January 1, 1994 to December 31, 2000. Infants with birth weight <2,500 g were classified as LBW. Logistic regression with robust variance estimation was performed to estimate the odds ratios of LBW per inter-quartile range increase in PM10. Results: The results showed that the odds ratios of term LBW per inter-quartile range increase in PM10 were 1.13 (95% CI: 1.02-1.25) during the first trimester and 1.10 (95% CI: 1.00-1.22) during the second trimester after adjustment for other important covariates, respectively. Conclusion: The findings of the study support the hypothesis that exposure to PM10 is associated with increased levels of term LBW. Further studies are warranted to corroborate these findings. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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