Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1 H-1,5-benzodiazepines.

Autor: Naqvi, Tahira, Mahajan, Deepali, Sharma, Rattan Lal, Khan, Inshad Ali, Kapoor, Kamal K.
Předmět:
Zdroj: Journal of Heterocyclic Chemistry; Jan2011, Vol. 48 Issue 1, p144-148, 5p, 2 Diagrams
Abstrakt: A series of novel 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}-3′-yl)-2-phenyl-2,3-dihydro-1 H-1,5-benzodiazepines were synthesized. These molecules were screened in vitro for their antifungal and antibacterial activity, and none of the tested compounds showed promising antimicrobial or antifungal activity. J. Heterocyclic Chem., 2011. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index