Rantes secreted from macrophages disturbs skeletal muscle regeneration after cardiotoxin injection in Cbl-b-deficient mice.

Autor: Kohno, Shohei, Ueji, Tatsuya, Abe, Tomoki, Nakao, Reiko, Hirasaka, Katsuya, Oarada, Motoko, Harada-Sukeno, Akiko, Ohno, Ayako, Higashibata, Akira, Mukai, Rie, Terao, Junji, Okumura, Yuushi, Nikawa, Takeshi
Zdroj: Muscle & Nerve; Feb2011, Vol. 43 Issue 2, p223-229, 7p
Abstrakt: The article focuses on the deficiency of the Cbl-b ubiquitin ligase gene activates macrophages in mice. It states that the study aimed to explain the pathophysiological roles of macrophages in muscle degeneration and regeneration in Cbl-b-deficient mice. It states that ablation of the Cbl-b gene expression delayed regeneration of cardiotoxininduced skeletal muscle damage compared with wild-type mice.
Databáze: Complementary Index