| Autor: |
Nonkin Avchen, Rachel, Wiggins, Lisa D., Devine, Owen, Van Naarden Braun, Kim, Rice, Catherine, Hobson, Nancy C., Schendel, Diana, Yeargin-Allsopp, Marshalyn |
| Předmět: |
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| Zdroj: |
Journal of Autism & Developmental Disorders; Feb2011, Vol. 41 Issue 2, p227-236, 10p, 2 Diagrams, 3 Charts |
| Abstrakt: |
We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI = 0.94, 0.99]), PPV (0.79 [CI = 0.66, 0.93]), and NPV (0.91 [CI = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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