Multi-centre, randomized clinical trial on the efficacy and safety of recombinant human platelet-derived growth factor with β-tricalcium phosphate in human intra-osseous periodontal defects.
| Autor: | Jayakumar, Avula, Rajababu, Palaparthi, Rohini, Surabhi, Butchibabu, Kalakonda, Naveen, Anumala, Reddy, Pathakota Krishnajaneya, Vidyasagar, Sisinty, Satyanarayana, Durvasula, Kumar, Sayini Pavan |
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| Předmět: |
PERIODONTIUM
BONE regeneration BONE resorption CALIBRATION CLINICAL trials DEBRIDEMENT DIAGNOSTIC imaging SURGICAL flaps LONGITUDINAL method MEDICAL cooperation COMPUTERS in medicine HEALTH outcome assessment PATIENT safety PLATELET-derived growth factor RESEARCH RESEARCH evaluation STATISTICAL sampling STATISTICAL hypothesis testing STATISTICS T-test (Statistics) SAMPLE size (Statistics) STATISTICAL significance BODY mass index TREATMENT effectiveness INTER-observer reliability DISEASE incidence BLIND experiment SURGERY |
| Zdroj: | Journal of Clinical Periodontology; Feb2011, Vol. 38 Issue 2, p163-172, 10p, 4 Color Photographs, 2 Black and White Photographs, 3 Charts, 4 Graphs |
| Abstrakt: | The article focuses on the efficiency and safety in human intra-osseous periodontal defects of recombinant human platelet-derived growth factor with ß-tricalcium phosphate. Fifty-four patients with periodontal osseous defects was involved in the double-blind, prospective, parallel, active-controlled, randomized, multi-centre clinical trial conducted by the authors, who evaluated the primary and secondary end points of treatment at third and sixth month. They conclude that rhPDGF-BB + ß-TCP is safe and effective for periodontal treatment. |
| Databáze: | Complementary Index |
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