Autor: |
Malfait, A.M., Butler, D.M., Presky, D.H., Maini, R.N., Brennan, F.M., Feldmann, M. |
Předmět: |
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Zdroj: |
Clinical & Experimental Immunology; Feb98, Vol. 111 Issue 2, p377, 7p, 2 Black and White Photographs, 3 Charts, 4 Graphs |
Abstrakt: |
Investigates the effect of blocking interleukin-12 (IL-12), a potent inducer of interferon-gamma and promoter of Th1 cell responses, during the induction phase of collagen-induced arthritis (CIA). Attenuation of the severity of arthritis during treatment with anti-IL-12; Effect of anti-IL-12 on serum levels of anti-CII antibodies; Effect of anti-IL-12 on spontaneous ex vivo cytokine production by synovial cells. |
Databáze: |
Complementary Index |
Externí odkaz: |
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