Obesity in African women in the North West Province, South Africa is associated with an increased risk of non-communicable diseases: the THUSA study.

Autor: Kruger, H. S., Venter, C. S., Vorster, H. H.
Zdroj: British Journal of Nutrition; Dec2001, Vol. 86 Issue 6, p733-740, 8p
Abstrakt: The objective of the present study was to assess the relationship between anthropometric measurements and risk factors for non-communicable diseases (NCD) in South African black women. A cross-sectional sample of 1040 apparently healthy black female volunteers, 15???70 years old, was recruited from thirty-seven randomly selected sites in the North West Province, stratified according to level of urbanisation. We analysed the association between BMI, waist:hip (WHR), waist circumference (WC) and skinfold measurements and the following risk factors for NCD: blood pressure, serum lipids, fasting serum glucose and insulin and plasma fibrinogen, by using age-adjusted correlation analyses and stepwise regression analysis. Of the subjects, 28??6 % were obese (BMI>30). After adjustment for age and smoking status, BMI correlated significantly with diastolic blood pressure (r 0??21, P=0??037), serum triacylglycerols (TG) (r 0??30, P=0??003), fasting glucose (r 0??29, P=0??005) and log fasting insulin (r 0??24, P=0??02). There was a significant negative correlation between BMI and HDL-cholesterol (r -0??38, P<0??001). Similar but stronger correlations were found between both WC and WHR and these risk factors. Together with age, WC was a significant predictor of TG, HDL-cholesterol and fasting glucose in regression analysis, while subscapular skinfold was a significant predictor of diastolic blood pressure and fasting glucose concentration. Triceps skinfold was a significant predictor of total serum cholesterol, LDL-cholesterol, plasma fibrinogen and the insulin sensitivity index. Measures of obesity, particularly WC, are associated with the risk for NCD in black South African women, in which a high rate of obesity has been found. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index