A multi-run chemistry module for the production of [[sup 18]F]FDG.

Autor: Sipe, B., Murphy, M., Best, B., Zigler, S., Lim, J., Dorman, E., Mangner, T., Weichelt, M.
Předmět:
Zdroj: AIP Conference Proceedings; 2001, Vol. 576 Issue 1, p808, 6p
Abstrakt: We have developed a new chemistry module for the production of up to four batches of [[sup 18]F]FDG. Prior to starting a batch sequence, the module automatically performs a series of self-diagnostic tests, including a reagent detection sequence. The module then executes a user-defined production sequence followed by an automated process to rinse tubing, valves, and the reaction vessel prior to the next production sequence. Process feedback from the module is provided to a graphical user interface by mass flow controllers, radiation detectors, a pressure switch, a pressure transducer, and an IR temperature sensor. This paper will describe the module, the operating system, and the results of multi-site trials, including production data and quality control results. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index