Light at night and breast cancer risk: results from a population-based case-control study in Connecticut, USA.

Autor: Li, Qian, Zheng, Tongzhang, Holford, Theodore, Boyle, Peter, Zhang, Yawei, Dai, Min, Holford, Theodore R
Předmět:
Zdroj: Cancer Causes & Control; Dec2010, Vol. 21 Issue 12, p2281-2285, 5p, 2 Charts
Abstrakt: Objective: To investigate the potential association between domestic exposure to light at night (LAN) and the risk of human breast cancer.Methods: A case-control study of female breast cancer was conducted in Connecticut. A total of 363 incident breast cancer cases and 356 age frequency-matched controls were interviewed using a standardized, structured questionnaire to obtain information on sleeping patterns and bedroom light environment. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by unconditional multivariate logistic regression.Results: A non-significantly increased risk of breast cancer was observed among postmenopausal women for those keeping lights on while sleeping (OR = 1.4, 95% CI 0.7, 2.7), those who reported mainly sleeping in the daytime (OR = 1.4, 95% CI 0.5, 4.3), and those not drawing the curtains/window shades while sleeping at night (OR = 1.2, 95% CI 0.8, 1.9).Conclusion: The results from this study suggest a potential increased risk of breast cancer associated with domestic exposure to LAN. Further studies with larger sample size are needed to confirm the results. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index