Glioblastoma multiforme in a mature ovarian teratoma with recurring brain tumours.

Autor: Yadav, A, Lellouch-Tubiana, A, Fournet, J C, Quazza, J E, Kalifa, C, Sainte-Rose, C, Jaubert, F
Předmět:
Zdroj: Histopathology; Aug99, Vol. 35 Issue 2, p170-173, 4p, 4 Black and White Photographs, 1 Chart
Abstrakt: Aims We report a case study to highlight the occurrence of glioblastoma multiforme in an ovarian teratoma. Methods and results A 10-year-old girl presented with a left frontal lobe primitive neuroectodermal tumour which was successfully treated. After 6 uneventful years, she developed glioblastoma multiforme located posterior to the site of the initial tumour. Six years later, she presented with a mature cystic teratoma containing glioblastoma multiforme. Conclusions Glioblastoma in an ovarian teratoma is an exceptional event, which might have an initial clinical presentation as a metastatic brain tumour. Alternatively, recurring glial tumours may occur in a genetically predisposed person; the role of radiation and chemotherapy in this context remains to be elucidated. [ABSTRACT FROM AUTHOR]
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