Current Problems Associated with Toxicity Evaluation of Medical Device Materials and Future Research Needs1.

Autor: NORTHUP, SHARON J.
Zdroj: Fundamental & Applied Toxicology; Oct1989, Vol. 13 Issue 2, p196-204, 9p
Abstrakt: The application of toxicology to the evaluation of medical device materials is reviewed. Strengths and weaknesses of systemic and local toxicity models are described. Developments needed to improve the methodology and predictability of assays for immunotoxicity and particulate toxicity are identified. Emerging methds are introduced for assessing adhesion, fibrosis, and blood compatibility. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index