| Autor: |
Krzeslowska, J., Rysz, J., Cierniewski, C. S., Luciak, M. |
| Zdroj: |
Nephrology Dialysis Transplantation; May1995, Vol. 10 Issue 5, p653-656, 4p |
| Abstrakt: |
In 14 chronic uraemic patients on regular haemodialysis treatment mean numbers of fibrinogen (Fg) receptors and glycoprotein IIb (GPIIb) molecules on one blood platelet were 8370±1282 and 15694±2102 respectively, and they were significantly lowered in comparison with those found in 14 healthy persons (37826±966 and 57994±6824 respectively). A high positive correlation was found between numbers of GPIIb molecules and those of Fg receptors both in chronic uraemic patients and healthy subjects. Four-month treatment of haemodialysis patients with recombinant human erythropoietin (rHuEpo) induced significant rises in haematocrit from 22.3±1.2 to 31.2±1.7%, blood platelet count from 164000±27000/μl to 206000±16000/μl and mean platelet volume from 7.08±0.29 fl to 8.26±0.22 fl. However, in haemodialysis patients numbers of the investigated surface platelet receptors, measured at 8 and 16 week of rHuEpo treatment, remained unchanged. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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